Preliminary Agenda

13 October, Rīga Stradiņš University 16 Dzirciema street, Great Hall

8:00-9:00Registration and networking  
9:00-10:00

Opening

John M. Tully, PMNET mentor
Daniels Pavļuts, Minister of Health of the Republic of Latvia
Raimonds Lapiņš, Deputy State Secretary on Economic Development, Ministry of Economics
Mārtiņš Staķis, Mayor of Riga Riga City Council

9:30-9:45Patient's story 
9:45-10:00Doctor's perspective 
10:00-10:30Break for refreshments and networking 
10:30-12:30

Cancer genetics and precision medicine

Sandra Lejniece (Latvia)
Rob Pieters  (The Netherlands)
10:30-10:45Rob PietersChief Medical Officer (CMO) at Princess Máxima Center for Pediatric Oncology and Professor of Pediatric Oncology at the University of Utrecht (The Netherlands)
Precision Medicine in the Princess Máxima Center for Pediatric Oncology
10:45-11:00David Gisselsson Nord, Division of Clinical Genetics; Principal investigator at LUCC: Lund University Cancer Centre (Sweden)Implementing nationwide whole genome sequencing for all children with cancer in Sweden
11:00-11:15Alwin Krämer, Full Professor at the University of Heidelberg and Director of the Clinical Cooperation Unit Molecular Hematology/Oncology of German Cancer Research Center (DKFZ) and Department of Internal Medicine, University of Heidelberg (Germany)Precision oncology approaches in cancer of unknown primary (CUP) 
11:15-11:30Martin Zoche, director at Molecular Tumor Profiling
Dept. of Pathology and Molecular Pathology, University Hospital Zurich and a Lecturer at the University of Zurich and Postgraduate Study Course in Pharmaceutical Medicine University of Duisburg-Essen  (Switzerland)
Homologous Recombination Deficiency (HRD) Testing in Clinical Practice
11:30-11:45 Juha Kononen, Chief Clinical Director, Docrates Cancer Clinic (Finland)
Precision oncology in clinical practice: successes and challenges


12:00-12:30Discussion  
12:30-13:30Lunch & Networking  
13:30-15:10

National diagnostics capacity - possibilities and challenges 

Gunta Purkalne (Latvia)
Karolis Šablauskas, (Lithuania)
13:30-13:45  Linda Gailīte, PhD, Head of the Laboratory, Leading Researcher, Scientific Laboratory of Molecular Genetics, Rīga Stradiņš University (Latvia)
Overview of genetic analysis methods used clinical medicine 
13:45-14:00 Ģirts Šķenders, East clinical university hospital , Laboratory Service (Latvia)Possibilities and challenges in molecular pathology at REUH
14:00-14:10 Inta Liepniece Karale, Associate Professor  at Rīga Stradiņš UniversityDepartment of Pathology, Pathologist at Riga East clinical university hospital, Laboratory Service  (Latvia)
TBC
14:10-14:20  Dmitrijs Rots, Molecular geneticist, Children's Clinical university hospital (CCUH) (Latvia)
Pediatric cancer molecular testing specifics and CCUH approach
14:20-14:30  E. Berga-Švītiņa and Anna Janberga, Molecular geneticist, Children's Clinical university hospital (Latvia)
Molecular testing of pediatric cancers: CCUH case examples.
14:30-14:40 Gunta Purkalne, PhD, MD, Professor at Rīga Stradiņš University, leading researcher at Department of Internal Medicine (Latvia)TBC
14:40-14:50 TBC, Children's Clinical university hospital in collaboration with Helsinki university hospital Pediatric oncology, approach from Children's clinical university hospital
14:50-15:10Roundtable Challenges and next steps 
15:10-15:40 Break for refreshments and networking  
15:40-17:30 

Precision medicine and biobanking

Janis Klovins (Latvia)
Lars O. Baumbusch (Norway)
15:40-15:55 Lars O. Baumbusch, Senior scientist at Department of Pediatric Research Division of  Paediatric and Adolescent Medicine Oslo University Hospital (Norway) The Norwegian Childhood Cancer Biobank - experiences and future perspectives 
15:55-16:10 Johanna Sandgren, PhD, Director, Barntumörbanken Department of Oncology-Pathology BioClinicum, Karolinska Institutet Karolinska University Hospital (Sweden)

The Swedish Childhood Tumor Biobank: A national sample collection and genomic characterization initiative of pediatric solid tumors for research purpose

16:10-16:30Jānis Klovins, Chairman of the Scientific Council of the Latvian Biomedical Research and Study Centre, Senior Researcher of the Latvian Biomedical Research and Study Centre, and Professor of Molecular Biology at the University of Latvia (Latvia)Biobank and Latvian Pediatric Cancer Initiative - project results
16:30-16:45Eero Punkka, Director at Helsinki Biobank   (Finland)The use of genomic biobank data in the personalized and preventive healthcare of biobank participants. 
16:45-17:00 Peeter Padrik, Associate Professor of Oncology at University of Tartu, medical oncologist, scientist and healthcare entrepreneur (Estonia)
Implementation of polygenic risk scores for personalized cancer prevention
17:00-17:15 Ilmārs Stonāns, Deputy Director at Institute of Clinical and Preventive Medicine, University of Latvia (Latvia)
The experience of Cancer biobanking at the Institute of Clinical and Preventive Medicine, University of Latvia and Riga East University Hospital
17:15-17:30  Q&A and Discussion 
17:30 Closing of Day I 

Parallel Session, Hall Senates


15:30-17:30

Roundtable on Education and competences

Moderated by: Juris Šteinbergs
Artūrs Ābols, BMC; Baiba Vilne, RSU, Karina Silina, SNF Prima group leader, ETH Zurich, Department of Chemistry and Applied Biosciences, Institute of Pharmaceutical Sciences, Ed Schuuring, Full Professor in Molecular Oncological Pathology, University Medical Center Groningen (TBC) and others TBC

14 October, Rīga Stradiņš University 16 Dzirciema street, Great Hall


8:00-8:30Networking 
8:30-9:30

Molecular tumor boards (MTB) - support for clinical decision making and education

  Martin Zoche (Switzerland)
8:30-8:45Martin Zoche, Director Molecular Tumor Profiling, Department of Pathology and Molecular Pathology University Hospital Zurich (Switzerland) Molecular Tumor Boards supports Clinical Decisions  
8:45-9:00Ed Schuuring, Full Professor in Molecular Oncological Pathology, University Medical Center Groningen  (The Netherlands)The Dutch experience using predictive profiling to guide targeted therapy in cancer patients: the role of our Molecular Tumor Board
9:00-9:15 Karolis Šablauskas, Hematologist, Hematology, Oncology and Transfusion Medicine Center Vilnius University Hospital Santaros Klinikos (Lithuania)
Personalizing treatment of acute myeloid leukemia, experience of Vilnius University Hospital Santaros Klinikos
9:15-9:35  Q&A and Discussion   
9:25-10:20

Systematic implementation of precision medicine 

 
9:25-9:40Katarina Puco, senior consultant oncologist working at Oslo University Hospital, Institute of Cancer Research as a study oncologist in IMPRESS- Norway study (Norway)Implementing Precession Medicine in Norway - IMPRESS Norway trial
9:40-9:55Vilja Pietiäinen, Researcher, Institute for Molecular Medicine Finland Precision Systems Medicine (Finland) Functional precision medicine for solid tumors
9:55-10:10Richard Rosenquist Brandell, Professor of Clinical Genetics at the Department of Molecular Medicine and Surgery, Karolinska Institutet and Senior Physician in Clinical Genetics at Karolinska University Hospital (Sweden) Genomic Medicine Sweden - implementing precision medicine in a regionally organized healthcare system
10:10-10:25

Thomas Hofmarcher, Research Director at IHE - The Swedish Institute for Health Economics (Sweden)

The Value of Precision Medicine in Oncology – the Case of Non-Small Cell Lung Cancer
10:25-10:35 Q&A and Discussion  
10:35-10:50Break for refreshments and networking  
10:50-11:10Denis Horgan, Chair, ICGC ARGO Independent Advisory Committee at International Cancer Genome Consortium; Executive Director, European Alliance for Personalised Medicine (Belgium)TBC
11:10-12:00

Roundtable with main healthcare sector stakeholders 

MoH, NHS
12:00-13:00Lunch & Networking 
13:00-14:00 

Shaping the future of research through healthcare data

Moderated by: Emil Syundyukov
13:00-13:15 Janek Metsallik, Digital Health Interoperability, Tallinn University of Technology (Estonia) Approaches to secondary use of data from Saudi-Arabia and Estonia  
13:15-13:30 Mārcis Leja,  Professor of Medicine, Director of the Institute of Clinical and Preventive Medicine, University of Latvia, Head of the Dept. of Research, Riga East University hospital (Latvia)Data collaborative on gastric cancer
13:30-13:40National Health service (Latvia), TBCTBC
13:40-14:00 Q&A 
14:00-14:15 Break for refreshments and networking  
14:15-15:15Roundtable with Ministry of Economics.

Data infrastructure for precision medicine

Moderator: 
Dāvids Fridmanis, PhD Senior Researcher Latvian Biomedical Research and Study Centre
Participants

  • Raimonds Lapiņš, Deputy State Secretary on Economic Development, Business Competitiveness, and Innovation of the Ministry of Economics of Latvia
  • Gatis Ozols, Deputy State Secretary on Digital Transformation issues
  • Aiga Balode, Deputy State Secretary. The Ministry of Health of the Republic of Latvia.
  • MSc Janek Metsallik, Digital Health Architect
  • Dr. sc. ing. Lauris Citkovskis, Head of HPC center (Riga Technical University)
  • Dr. sc. ing Renāte Strazdiņa, Customer Transformation and Innovation for Healthcare and Lifescience Lead EMEA at Microsoft
  • Dr. biol. Jānis Kloviņš, director of the Latvian Biomedical Research and Study Center

15:20-16:00Closing  
15:20-15:35 

Final remarks from round-table and panel discussions

  • Raimonds Lapiņš, Deputy State Secretary on Economic Development, Business Competitiveness, and Innovation of the Ministry of Economics of Latvia
  • Gatis Ozols, Deputy State Secretary on Digital Transformation issues
  • Aiga Balode, Deputy State Secretary. The Ministry of Health of the Republic of Latvia.
15:35-15:50Baiba Ziemele, Chairwoman of the Board, 
Chairwoman of the Board
Patient's Perspective 
15:50-16:00 Closing remarks 


Parallel Sessions, Hall Senates


9:20

Joint session with the Ministry of Economics of the Republic of Latvia and the Investment and Development Agency of Latvia

Mission-oriented approach for precision medicine evolution



More info

Moderator

Prof. Denis Horgan

Executive Director from the European Alliance of Personalised Medicine (EAPM)

Participants

  • Raimonds Lapiņš, Deputy State Secretary on Economic Development, Business Competitiveness, and Innovation of the Ministry of Economics of Latvia
  • Alvils Krams,  Chief specialist for pulmonology,  Assoc. prof. University of Latvia.

11:00-11:10 Break 
11:10-12:00 Presentation & Workshop  with the Ministry of Economics of the Republic of Latvia and the Investment and Development Agency of Latvia

Leveling up Biomedicine Ecosystem


More info

Moderator

Ieva Siliņa - Adviser to the Minister of Economics Ieva is also External Science and Education Policy Adviser to the President of Latvia and Former leader of Association of Latvian Young Scientists

Participants

  • Osvalds Pugovičs - Director of Organic Synthesis institute- TBC
  • Agrita Kiopa - Vice-Rector for Science (Rīga Stradiņš University)
  • Raimonds Lapiņš - Deputy State Secretary on Economic Development, Business Competitiveness, and Innovation of the Ministry of Economics of Latvia
  • Terje Peetso - head of the eHealth and ageing policy sector in the Unit on eHealth, Wellbeing and Ageing in the European Commission's DG CONNECT - TBC
  • Lauma Muižniece - Director of Latvian Council of Science, Latvia CERN ILO, Assistant professor

Presentation by D. Dimza-Jones, Deputy Head of Northern Powerhouse Life Sciences: Biotechnology & Pharmaceuticals Department for International Trade. Former Industry Facilitator at NIHR. Clinical Research Network Greater Manchester.

12:00-13:00Lunch & Networking  
13:00-14:00

Scientific session 
Scientific activities and projects

 
13:00-13:10Una Riekstiņa, University of Latvia, (Latvia)TBC
13:10-13:20Katrina Daila Neiburga, Rīga Stradiņš University (Latvia)RNA-seq in the molecular diagnosis of primary immunodeficiencies (PID)
13:20-13:30Ērika Bitiņa-Barlote, Rīga Stradiņš University (Latvia)Biomarkers for early diagnosis of bladder tumor (TBC)
13:30-13:40Nora Kriķe,  Rīga Stradiņš University (Latvia)Copy number variation and BRCA1/2 inactivation in breast cancer tissues
13:40-13:50Maksims Ivanovs, researcher at Institute of Electronics and Computer Science (Latvia)AI-assisted identification of precancerous gastric lesions
13:50-14:00Q/A and Discussion